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高效细胞洗濯,可最大化削减细胞丧失并供给抱负的检测机能

AquaMax® 微孔板洗板机是一个自力的体系,可设置装备摆设用于 96 和 384 孔微孔板。既可利用事后设置好的洗濯、浸泡和吸液法式,又可利用简洁的触摸屏界面来成立特性化的多步骤洗板法式。对生化检测,洗板机可去除未连系的物资和未反映的试剂。对细胞程度测定,该洗板机可供给 96 或 384 孔专业的细胞洗濯头,赐与懦弱的贴壁细胞暖和的洗濯。

  • 易于利用

    易于装置

    AquaMax洗板机的运转不须要内部泵和电脑,缩减了尝试台占空中积。可改换的洗濯头在几秒钟内便可装置完成,无需东西、校准或对齐。

  • 切确度

    无需停止孔板设置

    在一切孔中同时停止 96 和 384 孔吸液和分液,从而完成高精度检测和更快的微孔板处置,无需停止板孔设置或象限处置。

  • 高效

    运转多个洗濯打算

    用差别色彩标记的两个或四个洗液接口,与差别洗瓶的管子相婚配,方便缓冲液瓶和洗液瓶的疾速毗连,许可同时运转多个洗濯法式, 而无需切换差别范例的洗瓶。

AquaMax 微孔洗板机

AquaMax 微孔洗板机

特色

  • 轻松操纵

    按下按钮便可启动洗濯法式,轻松完成96孔和384孔微孔板的洗板。Standby选项可以或许使仪器处于待机筹办状况,针头浸在缓冲液中可以或许随时启动。

  • 方便性

    切确的分液和吸液节制,确保在不粉碎细胞的环境下停止处置。疾速、持续和底部洗濯设置可最大限制地延长洗濯时候。

  • 矫捷性

    经由过程轻松改换96 和 384 洗濯头和仪器主动探测洗濯头,可轻松设置装备摆设 AquaMax 洗板机,以知足以后和后续高精度的微孔板利用请求。

  • 主动化

    该款洗板机可与最新的主动化任务站轻松整合。它与 Molecular Devices StakMax® 微孔板堆板机和很多机器手臂处置器兼容。

经考证的 GxP 处置打算可确保数据完全性和合规性

咱们为 GMP/GLP 尝试室供给一整套颠末考证的合规性处置打算,可以或许赞助您疾速、自傲地成立合规尝试室。

  • 一流的微孔板读板机和洗板机可撑持您的一切尝试须要
  • IQ/OQ/PM 办事以数字化和合规格局保管仪器记实
  • 软件装置办事可考证并记实所需的组件是不是按操纵标准装置
  • 软件考证办事撑持美国食物药品监视办理局 (FDA) 21 CFR Part 11 指南
  • 接纳可追溯的考证板来查验您的微孔板读板机机能,赞助您取得靠得住成果
合用于 GMP-GLP 尝试室的 GxP 合规性处置打算

 

AquaMax 微孔读板机(酶标仪)的利用

AquaMax 微孔板洗板机的手艺参数和可选设置装备摆设

AquaMax 微孔板洗板机的相干资本

报告内容
视频和收集钻研会
抗原/免疫原发明和优化

免疫学和疫苗开辟任务流程

AquaMax 微孔洗板机

AquaMax 微孔洗板机

  • Number of Citations*: 99

    Latest Citations: For a complete list, please .

    *Source:

  • Citation
    Dated: Dec 01, 2017
    Publication Name: Muscle Stem Cells

    The hallmark of stem cells is their capability to either self-renew or to differentiate into a different cell type. Adult skeletal muscle contains a resident muscle stem cell population (MuSCs) known as satellite cells, which enables regeneration of damaged muscle tissue throughout most of adult life. During skeletal muscle regeneration, few MuSCs… View more

    The hallmark of stem cells is their capability to either self-renew or to differentiate into a different cell type. Adult skeletal muscle contains a resident muscle stem cell population (MuSCs) known as satellite cells, which enables regeneration of damaged muscle tissue throughout most of adult life. During skeletal muscle regeneration, few MuSCs self-renew to maintain the muscle stem cell pool while others expand rapidly and subsequently undergo myogenic differentiation to form new myofibers. However, like for other stem cell types, the molecular networks that govern self-renewal and/or differentiation of MuSCs remain largely elusive. We recently reported a method to isolate sufficient amounts of purified MuSCs from skeletal muscle which enables us to study their cell autonomous properties. Here, we describe a lentiviral, image-based loss-of function screening pipeline on primary MuSCs that enables systematic identification of genes that regulate muscle stem cell function.

    Contributors: Krishnamoorthy Sreenivasan, Thomas Braun, Johnny Kim  

  • Citation
    Dated: Feb 15, 2017
    Publication Name: Nature

    A highly protective malaria vaccine would greatly facilitate the prevention and elimination of malaria and containment of drug-resistant parasites1. A high level (more than 90%) of protection against malaria in humans has previously been achieved only by immunization with radiation-attenuated Plasmodium falciparum (Pf) sporozoites (PfSPZ)… View more

    A highly protective malaria vaccine would greatly facilitate the prevention and elimination of malaria and containment of drug-resistant parasites1. A high level (more than 90%) of protection against malaria in humans has previously been achieved only by immunization with radiation-attenuated Plasmodium falciparum (Pf) sporozoites (PfSPZ) inoculated by mosquitoes2,3,4; by intravenous injection of aseptic, purified, radiation-attenuated, cryopreserved PfSPZ (‘PfSPZ Vaccine’)5,6; or by infectious PfSPZ inoculated by mosquitoes to volunteers taking chloroquine7,8,9,10 or mefloquine11 (chemoprophylaxis with sporozoites). We assessed immunization by direct venous inoculation of aseptic, purified, cryopreserved, non-irradiated PfSPZ (‘PfSPZ Challenge’12,13) to malaria-naive, healthy adult volunteers taking chloroquine for antimalarial chemoprophylaxis (vaccine approach denoted as PfSPZ-CVac)14. Three doses of 5.12 × 104 PfSPZ of PfSPZ Challenge12,13 at 28-day intervals were well tolerated and safe, and prevented infection in 9 out of 9 (100%) volunteers who underwent controlled human malaria infection ten weeks after the last dose (group III). Protective efficacy was dependent on dose and regimen. Immunization with 3.2 × 103 (group I) or 1.28 × 104 (group II) PfSPZ protected 3 out of 9 (33%) or 6 out of 9 (67%) volunteers, respectively. Three doses of 5.12 × 104 PfSPZ at five-day intervals protected 5 out of 8 (63%) volunteers. The frequency of Pf-specific polyfunctional CD4 memory T cells was associated with protection. On a 7,455 peptide Pf proteome array, immune sera from at least 5 out of 9 group III vaccinees recognized each of 22 proteins. PfSPZ-CVac is a highly efficacious vaccine candidate; when we are able to optimize the immunization regimen (dose, interval between doses, and drug partner), this vaccine could be used for combination mass drug administration and a mass vaccination program approach to eliminate malaria from geographically defined areas.

    Contributors: Benjamin Mordmüller, Güzin Surat, Heimo Lagler, Sumana Chakravarty, Andrew S. Ishizuka, Albert Lalremruata, Markus Gmeiner, Joseph J. Campo, Meral Esen, Adam J. Ruben, Jana Held, Carlos Lamsfus Calle, Juliana B. Mengue, Tamirat Gebru, Javier Ibáñez, Mihály Sulyok, Eric R. James, Peter F. Billingsley, KC Natasha, Anita Manoj, Tooba Murshedkar, Anusha Gunasekera, Abraham G. Eappen, Tao Li, Richard E. Stafford, Minglin Li, Phil L. Felgner, Robert A. Seder, Thomas L. Richie, B. Kim Lee Sim, Stephen L. Hoffman & Peter G. Kremsner -Show fewer authors  

  • Citation
    Dated: Nov 01, 2014
    Publication Name: Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology

    Altered concentration of the vertebrate yolk protein precursor vitellogenin is a recognized biomarker for endocrine disruption in fish, and within recent years yolk protein alteration has also been associated with endocrine disruption in bivalves. Species-specific, direct and sensitive methods for quantification of vitellogenin in fish have been… View more

    Altered concentration of the vertebrate yolk protein precursor vitellogenin is a recognized biomarker for endocrine disruption in fish, and within recent years yolk protein alteration has also been associated with endocrine disruption in bivalves. Species-specific, direct and sensitive methods for quantification of vitellogenin in fish have been available for years whereas bivalve yolk protein levels have been estimated indirectly by alkali-labile phosphate (ALP) liberated from high molecular weight proteins because the sequence and biochemical structure of most bivalve yolk proteins are unknown. By applying a species-specific enzyme-linked immunosorbent assay (ELISA) for accurate determination of yolk protein level the impact of 17β-estradiol (57, 164 and 512 ng/L) on the freshwater bivalve Unio tumidus was investigated and compared with ALP estimations. Seven weeks of exposure during the pre-spawning and spawning period had no consistent effect on yolk protein concentration in hemolymph, and ALP levels in hemolymph also remained unchanged in both males and females. Further, basal male and female ALP levels were indistinguishable whereas the ELISA demonstrated that yolk protein levels of females exceeded male levels at the time of sampling, although male basal levels were high compared to fish. Altogether it is shown that individual ALP levels do not reflect yolk protein levels and hence hemolymph ALP levels cannot serve as biomarker for estrogenic exposure during the pre-spawning and spawning period in U. tumidus. The necessity of sensitive and validated biomarkers for reliable interpretation of data and the utility of ALP and yolk protein levels as biomarkers in bivalves are discussed.

    Contributors: Jane E. Morthorst, Henrik Holbech, Morten Jeppesen, Karin L. Kinnberg, Knud L. Pedersen, Poul Bjerregaard  

AquaMax® 微孔板洗板机

产物

产物编号:

AquaMax 2K 套装包含 AquaMax 2000 微孔板洗板机, 96 板洗濯头, 2 个带液位传感器的检测瓶, 和带传感器的 10L 废液瓶
AQUAMAX 2K
AquaMax 4K 套装包含 AquaMax 4000 微孔板洗板机, 96 板洗濯头, 4 个带液位传感器的检测瓶, 和带传感器的 10L 废液瓶 AQUAMAX 4K
StakMax 堆板机
STAKMAX
AquaMax 消毒剂
R8156
AquaMax 2000 洗板机的现场所规性保障 IQOQ 办事(装置认证/操纵认证办事,包含体系一切者认证记实的具体 IQOQ 成果)
AQ2000-IQOQSVC-OS
AquaMax 4000 洗板机的现场所规性保障 IQOQ 办事(装置认证/操纵认证办事,包含体系一切者认证记实的具体 IQOQ 成果)
AQ4000-IQOQSVC-OS

AquaMax 微孔板洗板机的相干产物和办事